Weihe Basin, which is wide in the east and narrow in the west, deep in the south and shallow in the north, is one of the typical Cenozoic grabens in Asia continent, connecting the Ordos block in the north, Qinling fold belt in the south, adjacent to the arcuate fault belt in the northeast margin of Tibet Plateau in the west and the Shanxi rift zone in the east. The Weihe Basin has experienced strong faulting and sedimentation since early Cenozoic, with many buried active faults developed. The nearly E-W-trending Taochuan-Huxian Fault is one of these faults. The middle-deep depth seismic profiling shows that the buried segment of Taochuan-Huxian Fault in Weihe Basin is located between the Qinling north margin fault and the Weihe Fault and it is a fundamental fault that cuts through the Palaeozoic stratum and divides the Xi'an depression into two parts. To explore and know the location and structural characteristics of the Taochuan-Huxian fault segment hidden in the Weihe Basin and its activity in the Late Quaternary is of important significance for the researches of seismo-tectonic structure and seismic hazard of strong earthquakes in the study region. For this purpose, we deployed 7 profiles for shallow seismic reflection surveys, relied on the “Xingping Active Fault Project”. Based on these surveys, we determined the existence and hidden positions of the Taochuan-Huxian Fault and its branches in the Weihe Basin by combining with the data from some existing seismic reflection profiles of shallow-depths and middle-deep depths. Our research suggests that the Taochuan-Huxian Fault(F8)is connected to the southern margin fault of the Taibai Basin in the west, and eastward, passes through the northern margin of the Qinling Mountains and enters into the Weihe Basin at the town of Tangyu, Zhouzhi County, and then is concealed under the loose sediment in the Weihe Basin. The strike direction of this fault is northeast when crossing obliquely through the town of Zhouzhi County, then gradually turns to a nearly east-west direction between Zhouzhi and Huxian, showing a northward convex bend in the fault trace buried in the basin. Further eastward, the Taochuan-Huxian Fault(F8)connects to the Tieluzi Fault near the town of Yinzhen, Huxian County. In addition, a buried antithetic fault(DF3)(also a secondary branch)of the buried Taochuan-Huxian Fault(F8)is found between the north of Zhouzhi and the north of Huxian, and it extends roughly parallel to F8 under the loose sediment. This research also reveals that in the central portion of the Weihe Basin, the northern margin fault of the Qinling Mountains, the Weihe Fault and the Taochuan-Huxian Fault, together with their branch faults, constitute a large-scale fault zone with the tectonic feature of negative flower structure, as known from the interpreted cross-sections; among them, the F8 and DF3 faults and their secondary strands consist of a relatively small-scale negative flower structure. By combining with relevant information such as that from a composed cross-section using geological logs of multiple boreholes, and so on, we concluded that, within the study region of this research, the fault zone with the buried F8 fault as its principal fault was active at least in the late Pleistocene, and hence is an active fault zone. Finally, the reason is discussed in this article for the faults, mentioned above, in the Weihe Basin that show the tectonic pattern of negative flower structure, instead of that of stair-stepping or ladder structure, and one possible interpretation is proposed that the dominant motion of these active faults are not normal faulting, but sinistral strike-slip faulting. Since the Cenozoic, the subduction of the Indian plate to the Eurasian plate caused the Tibet Plateau to be pushed out to the northeast and blocked by the Ordos block. Because of obstruction in the north, the material flows eastward along Qinling Mountains in the south, resulting in the extrusion shearing effect on the Weihe Basin in the middle. In addition, recent seismic and geological studies have discovered that many active faults in Weihe Basin and its edges are obviously of sinistral strike-slip, which also proves that the movement of these active faults in the basin is not dominated by normal faulting, but sinistral strike-slipping.