On April 14th,2010,a strong earthquake of MS 7.1 hit the Yushu County in Qinghai Province,which brought about a large number of casualties and economic losses.Based on the three times of investigation to the quake-hit area,and the analysis of natural environment,humanities and social economical conditions,the general characteristics of the earthquake hazard are summarized from the point of view of origin of earthquake disaster,emergency rescue and reconstruction. There are the following factors that make the disaster serious and the rescue operation and reconstruction more difficult,such as,the overlapping of epicenter with residential quarters and the fault-controlled damage distribution. Consequently, the damage is serious and the quake-hit area is large,and the severely affected areas are concentrated; The environment in Yushu is harsh,high in attitude,cold and oxygen deficient,thus the relief was difficult; The low anti-seismic ability of buildings there makes the destruction more serious; The lifeline infrastructures are vulnerable and inadequate,and the damage to them caused large associated damage; The buildings and population in urban area are dense,which partly led to the lack of shelters; People commonly have a poor education and can't speak Chinese,thus difficult to communicate.In addition,there is lack of knowledge of earthquake disaster prevention and reduction,thus affecting the efficiency of disaster relief.The factors that are beneficial to earthquake disaster reduction,emergency rescue and reconstruction are: Tents can easily be acquired owing to the living habit of the nomadic peoples,so people there can accommodate themselves to the particular circumstances; The Yushu area has a strong religious atmosphere,and the local monks and temples have played an important role in the earthquake relief work.Finally,this paper comes up with some experience and revelations about the earthquake disaster reduction in Qinghai-Tibet Plateau preliminarily.